![]() ![]() Currently, this debridement antibiotic bead and retention of the implant (DABRI) procedure is an popular treatment for post-TKA PJI. Other advantages include a higher local antibiotic concentration, reduced biofilm formation, lowered risk of chronic infection, and protection of implants against bacterial colonization. In addition, the use of antibiotic calcium sulfate beads reduces side effects and toxicity caused by systemically administered drugs. The reported success rates varied from 18 to 100%, depending on the duration of symptoms, time to debridement, type of microorganisms involved, debridement technique used, type of antibiotic, and duration of antibiotic therapy. Debridement, antibiotics, and implant retention (DAIR) is an effective therapeutic option for acute PJI. Īccording to the Musculoskeletal Infection Society criteria, post-TKA PJIs are classified into acute postoperative, acute hematogenous, and late chronic infection. Currently, surgical management remains challenging and has a major impact on the patients. The incidences of post-TKA PJI reportedly ranged from 0.5 to 2%. Periprosthetic joint infection (PJI) represents one of the most difficult complications after total knee arthroplasty (TKA). Randomized controlled studies are warranted for the routine use. Additional use of calcium sulfate beads was safe, but might not improve the treatment result. Conclusionīoth DAIR and DABRI could be used to treat acute periprosthetic joint infections and the outcomes and treatment costs of the two procedures were comparable. A significant difference was found in the follow-up period between the two groups ( P<0.05). There were no significant differences in patient age ( P>0.05), the Musculoskeletal Infection Society score ( P>0.05), and success rate ( P>0.05). The mean age of DABRI group ( n=17) was 64 years, with 10 patients being male and 7 female. The mean follow-up period lasted 30 months. The mean age of DAIR group ( n=15) was 69 years, with 7 being male, and 8 female. ![]() ![]() Patient age, the Musculoskeletal Infection Society score, microorganisms involved, and success rate were assessed. During the DABRI, additional calcium ulphate antibiotic beads were used. The patients were divided into a DAIR group ( n=15) and a DABRI group ( n=17). Methodīetween 20, 32 patients with acute periprosthetic joint infection who were treated by total knee arthroplasty were retrospectively reviewed. debridement antibiotic bead and retention of the implant (DABRI) in terms of infection-free success rate and treatment cost for acute periprosthetic joint infections after total knee arthroplasty (TKA). The study aimed to compare debridement, antibiotics, and implant retention (DAIR) vs. ![]()
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